Amisulpride treating manufactured

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Amisulpride treating manufactured

Post  jiangxiao on Sun Aug 21, 2011 5:51 am

Amisulpride is manufactured by Lorex-Synthelabo under the trade name Solian. Tablets are available in 50 mg or 200 mg formats. The recommended doses are between 400 mg/day and 800 mg/day. Amisulpride appears to be effective against negative symptoms at low doses e.g. 100 mg daily.
Amisulpride is a second generation antipsychotic, a substituted benzamide. Amisulpride appears to be an effective agent in treating schizophrenia for what are characterised as positive and negative symptoms. The recommended doses are between 400 mg/day and 800 mg/day. Amisulpride demonstrates a good global safety profile, particularly when compared with first generation antipsychotics, such as haloperidol. There are interesting studies that point towards amisulpride's antidepressant effect in dysthymia and one could speculate on possible roles in affective psychoses and chronic fatigue syndrome.
Further work from this French group compared amisulpride and amineptine with placebo, (Boyer et al, 1999). During this 3-month study of 323 patients, amisulpride (50 mg/day) was compared to amineptine (200 mg/day) in the treatment of primary dysthymia. Both amisulpride and amineptine were found to be statistically superior to placebo on the Clinical Global Impression (item 2), Montgomery-Asberg Depression Rating Scale and the Scale for the Assessment of Negative Symptoms.
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